Figure 3.

The effect of Rab GTPase downregulation in EBV-encoded capsid antigen p18 expression. Rab8a, Rab10, and Rab11a were downregulated in Akata⁺ cells using siRNAs. After 48 h of treatment with αhIgG for the EBV lytic cycle induction, and the semi-quantification of the EBV-encoded capsid, antigen p18 was performed by Western blot. (A) The representative data are shown. (B) Normalized p18 expression values to the reference α tubulin are shown. Results are representative of independent experiments conducted three times and the average and standard deviations values are shown. Statistical differences were assessed using Student’s t test and are represented as * p < 0.05 versus respective control.