Figure 2.

Whole-genome multilocus typing-based phylogenetic analysis of three environmental E. coli O45:H16 strains (RM13745, RM11911, and RM13752) and one clinical E. coli O45:H2 strain (SJ7) with eleven reference strains. The phylogenetic tree indicates five distinct clusters, with the strain names shown in black color for cluster 1, green color for cluster 2, purple color for cluster 3, blue cluster for cluster 4, and orange color for cluster 5. The strains highlighted in yellow were sequenced this study. The sources of isolation (outbreak, clinical, and environmental) for these 15 strains are indicated right next to the strain names.