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. 2020 Jun 10;14:23. doi: 10.1186/s40246-020-00271-7

Table 3.

Significantly enriched pathway

Gene set name[#Genes(K)] Description #Genes in Overlap(k) p value FDR q value
REACTOME_INTERFERON_GAMMA_SIGNALING[63] Interferon gamma signaling 5 2.61E−09 2.81E−06
KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION[89] Antigen processing and presentation 5 1.52E−08 8.16E−06
KEGG_ALLOGRAFT_REJECTION[38] Allograft rejection 4 3.55E−08 1.28E−05
KEGG_GRAFT_VERSUS_HOST_DISEASE[42] Graft-versus-host disease 4 5.35E−08 1.40E−05
KEGG_TYPE_I_DIABETES_MELLITUS[44] Type I diabetes mellitus 4 6.51E−08 1.40E−05
KEGG_CELL_ADHESION_MOLECULES_CAMS[134] Cell adhesion molecules (CAMs) 5 1.19E−07 2.13E−05
KEGG_AUTOIMMUNE_THYROID_DISEASE[53] Autoimmune thyroid disease 4 1.40E−07 2.15E−05
REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE[14] Translocation of ZAP-70 to immunological synapse 3 2.21E−07 2.97E−05
REACTOME_INTERFERON_SIGNALING[159] Interferon signaling 5 2.78E−07 3.32E−05
REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS[16] Phosphorylation of CD3 and TCR zeta chains 3 3.39E−07 3.66E−05