Table 1.
Clinical characteristics of CF patients according to their bacteriological status.
| SA alone (%) | PA alone (%) | SA and PA | ||||
|---|---|---|---|---|---|---|
| Competition | Coexistence | Merge | p_value* | |||
| Number | 112/212 (52.83) | 48/212 (22.64) | 18/52 (34.61) | 34/52 (65.38) | 52/212 (24.53) | |
| Age (years) | 16.49 ± 8.77 | 32.02 ± 13.82 | 23.67 ± 8.98 | 23.24 ± 10.52 | 23.38 ± 9.93 | <0.0001a |
| ≥18 years | 45/112 (40.18) | 42/48 (87.50) | 14/18 (77.78) | 23/34 (64.65) | 37/52 (71.15) | |
| Sex, male | 63/112 (56.25) | 23/48 (47.92) | 10/18 (55.6) | 13/34 (38.24) | 23/52 (44.23) | ns |
| Genotype | ||||||
| Moderate | 26/112 (23.21) | 9/48 (18.75) | 3/18 (16.67) | 3/34 (8.82) | 6/52 (11.54) | ns |
| Severe | 86/112 (76.79) | 39/48 (81.25) | 15/18 (83.33) | 31/34 (91.18) | 46/52 (88.46) | |
| BMI (kg/m2) | 18.06 ± 2.68 | 20.74 ± 2.42 | 19.25 ± 2.56 | 19.71 ± 3.56 | 19.55 ± 3.23 | <0.0001a |
| Undernourishment | 11/112 (9.82) | 1/48 (2.08) | 1/18 (5.56) | 3/34 (8.82) | 4/52 (7.69) | ns |
| Oral food supplementation | 23/112 (20.54) | 13/48 (27.08) | 3/18 (16.67) | 15/34 (44.12) | 18/52 (34.62) | ns |
| Enteral nutrition | 4/112 (3.57) | 0/48 (0) | 0/18 (0) | 4/34 (11.76) | 4/52 (7.69) | ns |
| Pancreatic insufficiency | 101/112 (90.18) | 45/48 (93.75) | 17/18 (94.44) | 33/34 (97.06) | 50/52 (96.15) | ns |
| CF-related diabetes | 9/112 (8.04) | 14/48 (29.17) | 3/18 (16.67) | 10/34 (29.41) | 13/52 (25.00) | 0.0007b |
| Cirrhosis | 6/112 (5.36) | 2/48 (4.17) | 0/18 (0) | 1/34 (2.94) | 1/52 (1.92) | ns |
| Hospitalizations | ||||||
| Number | 17/112 (15.18) | 18/48 (37.50) | 6/18 (33.33) | 14/34 (41.18) | 20/52 (38.46) | 0.0003a |
| Length | 8.00 ± 6.10 | 17.39 ± 14.39 | 7.33 ± 6.12 | 29.14 ± 27.39 | 22.60 ± 25.06 | 0.0002a |
| Number of exacerbations | 0.25 ± 0.69 | 1.44 ± 1.37 | 1.28 ± 1.60 | 1.35 ± 1.50 | 1.33 ± 1.52 | <0.0001a |
| FEV1 (% predicted) | 85.87 ± 22.39 | 55.09 ± 18.64 | 59.72 ± 18.73 | 64.59 ± 21.79 | 62.90 ± 20.73 | <0.0001a |
BMI, Body Mass Index; FEV1, Forced Expiratory Volume in one second.
*
P values from comparison between three groups: SA vs. PA vs. SA+PA (merge).
a
P values from Kruskal-Wallis non-parametric test for comparison of the three groups (continuous variables).
b
P values from Fisher's exact test for comparison of the three groups (categorical variables).