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. 2020 Jun 9;9:66. doi: 10.1186/s40249-020-00681-8

Table 1.

Comparison of nodule characteristics between lung metastasis and hematogenous disseminated tuberculosis

Lung metastasis [35, 36] Hematogenous disseminated tuberculosis (HDTB) [37, 38]
Sources Hematogenous Hematogenous
Cancer history Yes No
Anatomical distribution Scatter within two lung fields, but mostly distribute in the middle and lower lung field and surround subpleural lung tissues. Acute HDTB Subacute or chronic HDTB
Randomly and evenly distribute in both lung fields Randomly scatter in the two lung fields without uniformity the upper middle lung is more common
Nature Solid density, ground glass density, or mixed density Uniform density Uneven density, may display tuberculous globules, or tuberculoma
Size Variable Uniform size, more miliary nodules Variable
Boundary Most of nodules have clear boundaries, but part of them not, showing cavity or ground glass opacity Clear Not clear, may display cavity or ground glass opacity
Accompanying symptoms Mediastinal lymph node enlargement and pleural effusion Mediastinal lymph node enlargement