Table 1.
Characteristic | High-dose group (n = 55) | Low-dose group(n = 58) | All cases (n = 113) | |
---|---|---|---|---|
Age (years) | Median | 67 | 62.5 | 65 |
Range | 49–83 | 36–83 | 36–83 | |
Gender | Male | 24 | 21 | 45 |
Female | 31 | 37 | 68 | |
Performance status | 0 | 35 | 33 | 68 |
1 | 18 | 24 | 42 | |
2 | 2 | 1 | 3 | |
Primary site | Colorectum | 20 | 8 | 28 |
Uterine cervix | 9 | 18 | 27 | |
Endometrium | 5 | 10 | 15 | |
Ovary | 8 | 2 | 10 | |
Urothelial | 4 | 4 | 8 | |
Others | 9 | 16 | 25 | |
Histopathology | Adenocarcinoma | 41 | 31 | 72 |
Squamous cell carcinoma | 10 | 23 | 33 | |
Others | 4 | 4 | 8 | |
Initial category | T-category 1:2:3:4 | 13:20:18:4 | 18:13:19:8 | 31:33:37:12 |
N-category positive | 32 | 32 | 64 | |
Duration from initial diagnosis (months) | Median | 25.4 | 22.4 | 24.1 |
Range | 2.9–102.4 | 1.9–100.4 | 1.9–102.4 | |
DFI (months) | Median | 8.7 | 8.3 | 8.5 |
Range | 0.6–64.4 | 0.5–86.6 | 0.5–86.6 | |
Radiation therapy method | 3DCRT | 12 | 35 | 47 |
SBRT&IMRT | 43 | 23 | 66 | |
LN site | Para-aortic | 29 | 43 | 72 |
Iliac | 8 | 10 | 18 | |
Presacral | 9 | 3 | 12 | |
Obturator | 9 | 2 | 11 | |
Extra-regional LN for primary site | no | 37 | 28 | 65 |
yes | 18 | 30 | 48 | |
Number of lymph node | 1 | 33 | 28 | 61 |
2–5 | 22 | 30 | 52 | |
LN size (cm) | Median | 2 | 2 | 2 |
Range | 1–5.5 | 1–5 | 1–5.5 | |
Prophylactic nodal irradiation | no | 40 | 29 | 69 |
yes | 15 | 29 | 44 | |
Chemotherapy | no | 15 | 7 | 22 |
yes | 40 | 51 | 91 | |
Concurrent chemotherapy | no | 43 | 37 | 80 |
yes | 12 | 21 | 33 | |
EQD2 (Gy) | Median | 66.6 | 50 | 59.7 |
Range | 60.4–101.4 | 40.3–59.8 | 40.3–101.4 | |
Follow-up time of entire group (months) | Median | 20.2 | 15.9 | 17.8 |
Range | 5.8–84.7 | 3.7–109.8 | 3.7–109.8 | |
Follow-up time in surviving patients (months) | Median | 23 | 24.2 | 23.7 |
Range | 7.6–84.7 | 4.0–109.8 | 4.0–109.8 |
n number of patients, LN lymph node, DFI disease-free interval, 3DCRT 3-dimentional conformal radiation therapy, SBRT Stereotactic Body Radiation Therapy, IMRT intensity-modulated radiation therapy, EQD2 equivalent dose in 2 Gy fraction