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. 2020 Jun 9;20:540. doi: 10.1186/s12885-020-07033-7

Table 1.

Patient characteristics

Characteristic High-dose group (n = 55) Low-dose group(n = 58) All cases (n = 113)
Age (years) Median 67 62.5 65
Range 49–83 36–83 36–83
Gender Male 24 21 45
Female 31 37 68
Performance status 0 35 33 68
1 18 24 42
2 2 1 3
Primary site Colorectum 20 8 28
Uterine cervix 9 18 27
Endometrium 5 10 15
Ovary 8 2 10
Urothelial 4 4 8
Others 9 16 25
Histopathology Adenocarcinoma 41 31 72
Squamous cell carcinoma 10 23 33
Others 4 4 8
Initial category T-category 1:2:3:4 13:20:18:4 18:13:19:8 31:33:37:12
N-category positive 32 32 64
Duration from initial diagnosis (months) Median 25.4 22.4 24.1
Range 2.9–102.4 1.9–100.4 1.9–102.4
DFI (months) Median 8.7 8.3 8.5
Range 0.6–64.4 0.5–86.6 0.5–86.6
Radiation therapy method 3DCRT 12 35 47
SBRT&IMRT 43 23 66
LN site Para-aortic 29 43 72
Iliac 8 10 18
Presacral 9 3 12
Obturator 9 2 11
Extra-regional LN for primary site no 37 28 65
yes 18 30 48
Number of lymph node 1 33 28 61
2–5 22 30 52
LN size (cm) Median 2 2 2
Range 1–5.5 1–5 1–5.5
Prophylactic nodal irradiation no 40 29 69
yes 15 29 44
Chemotherapy no 15 7 22
yes 40 51 91
Concurrent chemotherapy no 43 37 80
yes 12 21 33
EQD2 (Gy) Median 66.6 50 59.7
Range 60.4–101.4 40.3–59.8 40.3–101.4
Follow-up time of entire group (months) Median 20.2 15.9 17.8
Range 5.8–84.7 3.7–109.8 3.7–109.8
Follow-up time in surviving patients (months) Median 23 24.2 23.7
Range 7.6–84.7 4.0–109.8 4.0–109.8

n number of patients, LN lymph node, DFI disease-free interval, 3DCRT 3-dimentional conformal radiation therapy, SBRT Stereotactic Body Radiation Therapy, IMRT intensity-modulated radiation therapy, EQD2 equivalent dose in 2 Gy fraction