Table 3.
ABTS Free Radicals Scavenging Activity Results
| Compound Name | Conc. μg/mL | (%) Inhibition | IC50 (μM) |
|---|---|---|---|
| (S)-1-(2,5-dioxo-1-phenylpyrrolidin-3-yl) cyclohexanecarbaldehyde | 1000 | 79.87±1.27*** | 332.94 |
| 500 | 67.31±0.58*** | ||
| 250 | 61.22±1.28*** | ||
| 125 | 54.49±0.60*** | ||
| 62.5 | 40.51±0.54*** | ||
| 31.25 | 26.87±0.85*** | ||
| 15.62 | 16.60±1.63*** | ||
| (R)-2-((S)-2,5-dioxo-1-phenylpyrrolidin-3-yl)-2-phenylpropanal | 1000 | 75.76±0.61*** | 497.82 |
| 500 | 68.51±0.54*** | ||
| 250 | 59.87±0.85*** | ||
| 125 | 49.31±0.58*** | ||
| 62.5 | 38.10±0.90*** | ||
| 31.25 | 22.83±1.21*** | ||
| 15.62 | 12.33±1.67*** | ||
| Ascorbic acid (Std.) | 1000 | 87.73±0.78 | 85.17 |
| 500 | 81.70±1.60 | ||
| 250 | 75.03±0.23 | ||
| 125 | 67.00±0.00 | ||
| 62.5 | 58.00±1.15 | ||
| 31.25 | 52.67±0.89 | ||
| 15.62 | 46.00±0.58 |
Notes: Values represent % radical scavenging (mean ± SEM) of three replicates. Values significantly different as compare to positive control, ***P < 0.001.