Table 4.
Hydrogen per Oxide (H2O2) Free Radicals Scavenging Activity Result
| Compound Name | Conc. μg/mL | (%) Inhibition | IC50 μM |
|---|---|---|---|
| (S)-1-(2,5-dioxo-1-phenylpyrrolidin-3-yl) cyclohexanecarbaldehyde | 1000 | 79.58±1.12 | 45 |
| 500 | 72.90±0.96 | ||
| 250 | 68.77±1.24 | ||
| 125 | 58.76±0.71 | ||
| 62.5 | 44.90±1.55*** | ||
| 31.25 | 34.42±0.43*** | ||
| 15.62 | 28.03±0.35*** | ||
| (R)-2-((S)-2,5-dioxo-1-phenylpyrrolidin-3-yl)-2-phenylpropanal | 1000 | 71.77±1.24*** | 145 |
| 500 | 65.08±0.47*** | ||
| 250 | 55.76±0.71*** | ||
| 125 | 47.80±1.50*** | ||
| 62.5 | 41.90±0.96*** | ||
| 31.25 | 34.03±0.35*** | ||
| 15.62 | 28.80±1.50*** | ||
| Acarbose (Std) | 1000 | 83.62±1.67 | 26 |
| 500 | 75.08±1.04 | ||
| 250 | 71.95±2.01 | ||
| 125 | 63.87±1.27 | ||
| 62.5 | 57.67±0.88 | ||
| 31.25 | 49.90±0.48 | ||
| 15.62 | 41.80±0.37 |
Notes: The data is represented as mean ± SEM, (n=3). Values were significantly different as compared to the positive control, ***P<0.001 (highly significant)