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. 2020 May 13;20(1):810–816. doi: 10.3892/ol.2020.11608

Figure 2.

Figure 2.

ROS generation in MDA-MB-468 cells is increased following propofol exposure. (A) Intracellular ROS production in MDA-MB-468 cells was measured using a DCF-DA assay. MDA-MB-468 cells were treated with PBS (control) or propofol (5, 10, 20 and 20 µM + NAC) for 24 h. Cellular ROS production was observed using an inverted fluorescence microscope. (B) Quantification of ROS production following propofol treatment. Data are presented as the mean ± SD (n=3). *P<0.05 and **P<0.01 vs. the control group. Compared with the 20 µM group, the 20 µM + NAC group showed a significant difference (##P<0.01). ROS, reactive oxygen species; NAC, N-acetyl-L-cysteine.