Table I.
Association between CLDN10 expression and clinicopathological characteristics of patients with ovarian cancer.
| CLDN10 expression | |||||
|---|---|---|---|---|---|
| Clinical factor | High (n=133) | Low (n=133) | Total (n=266) | 95% CI | P-value |
| Mean age ± SD, years | 57.14±10.47 | 60.9±11.04 | 1.1513–6.3675 | 0.0049 | |
| Tumor pathological stage, n | |||||
| Stage I–II | 9 | 11 | 20 | 0.4495–3.5211 | 0.8167 |
| Stage III–IV | 123 | 121 | 244 | ||
| Grade, n | 2.8688–3.0024 | ||||
| G1 | 0 | 1 | 1 | 0.8200 | |
| G2 | 15 | 17 | 32 | ||
| G3 | 113 | 111 | 224 | ||
| G4 | 0 | 1 | 1 | ||
| GB | 1 | 1 | 2 | ||
| GX | 3 | 1 | 4 | ||
| Primary site, n | 0.3413–0.5238 | ||||
| Bilateral | 95 | 85 | 180 | 0.6890 | |
| Left | 16 | 19 | 35 | ||
| Right | 18 | 19 | 37 | ||
| Tumor status | 0.7075–1.8518 | ||||
| Tumor-free | 34 | 25 | 59 | 0.6426 | |
| With tumor | 83 | 91 | 174 | ||
| Vascular invasion indicator | 0.3081–2.1570 | ||||
| Yes | 15 | 18 | 33 | 0.6596 | |
| No | 21 | 31 | 52 | ||
| Mean disease-free survival time ± SD, months | 20.74±20.23 | 17.139±12.62 | −7.4010–0.2000 | 0.0633 | |
| Mean overall survival time ± SD, months | 40.976±30.86 | 31.271±22.46 | −16.5740(−)-2.8350 | 0.0058 | |
| Longest dimension, cm | 1.353077 | 1.485833 | 0.0087–0.27426 | 0.0658 | |
CLDN10, claudin 10.