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. 2020 May 13;20(1):751–757. doi: 10.3892/ol.2020.11610

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Copyright: © Zong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Overexpression of MAP3K1 reverses the effect of miR-203 mimic on cell proliferation, apoptosis and invasion. (A) miR-203 and MAP3K1 expression in TE-1 cells following transfection with miR-203 mimic and the MAP3K1 overexpression plasmid. Overexpression of MAP3K1 reversed the (B) inhibitory effect of miR-203 mimic on cell proliferation, (C) promotive effect of miR-203 mimic on cell apoptosis and (D) inhibitory effect of miR-203 mimic on cell invasion. Data are analyzed using one-way analysis of variance, followed by Student-Keuls-Neuman test. *P<0.05, ^#P<0.01 vs. control (miR-negative control + empty vector); **P<0.05 vs. miR-203 mimic group. MAP3K1, Mitogen-Activated Protein Kinase Kinase Kinase 1; miR, microRNA.