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. 2020 Apr 21;20(1):145–154. doi: 10.3892/ol.2020.11556

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Induction of pyroptosis with dasatinib in SH-SY5Y and A549 cells. (A) Morphological changes in the DOX or dasatinib-induced pyroptosis. One representative result from three independent experiments is shown. (B) Levels of LDH release in the culture supernatant after exposure to DOX. Levels of LDH after exposure to dasatinib in (C) SH-SY5Y cells and (D) A549 cells. *P<0.05, **P<0.01 represents the drug treated groups vs. control group. DOX, doxorubicin; Ctrl, control; LDH, lactate dehydrogenase.