Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 8;79(6):811–818. doi: 10.1136/annrheumdis-2020-216942

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Hypothetic model of shear force-induced horizontal fissures in osteoarthritis (OA) patients with obesity. Osteochondral unit is a multiphasic materials structure. The unit may receive direct loading from cartilage to subchondral bone (SCB) in OA patients with normal weight. However, in patients with obesity, articular cartilage (AC) experiences a large lateral deformation due to the high compressive stress, the deformation being restrained by the underlying calcified cartilage (CC) and SCB, which generates secondary shear stress to induce horizontal fissures and cartilage erosion at the osteochondral interface.