Table 2.
RAMP3 genotype frequencies in the PEAK-25 and OPRA cohorts.
| SNP & Alleles | PEAK-25 |
OPRA |
||||||
|---|---|---|---|---|---|---|---|---|
| Homozygotes Major Allele No. (%) |
Heterozygotes No. (%) |
Homozygotes Minor Allele No. (%) |
MAF | Homozygotes Major Allele No. (%) |
Heterozygotes No. (%) |
Homozygotes Minor Allele No. (%) |
MAF | |
| rs3757575 (G/A) | 592 (59.3%) |
365 (36.5%) |
42 (4.2%) |
0.23 | 622 (62.3%) |
334 (33.4%) |
43 (4.3%) |
0.21 |
| rs2074654 (T/C) | 905 (90.3%) |
93 (9.3%) |
4 (0.4%) |
0.05 | 933 (93.2%) |
65 (6.5%) |
3 (0.3%) |
0.04 |
| rs1294935 (T/C) | 260 (26.0%) |
484 (48.4%) |
255 (25.5%) |
0.50 | 234 (23.4%) |
496 (49.7%) |
268 (26.9%) |
0.48 |
| rs11982639 (C/G) | 594 (59.4%) |
340 (34.0%) |
66 (6.6%) |
0.24 | 617 (61.9%) |
332 (33.3%) |
48 (4.8%) |
0.21 |
| rs12702121 (A/G) | 595 (59.4%) |
341 (34.0%) |
66 (6.6%) |
0.24 | 619 (61.8%) |
334 (33.3%) |
49 (4.9%) |
0.22 |