Table 1.
Median lethal dose (μg/g mouse) and percentage of crotoxin homologs found in venoms of C. simus, C. culminatus and C. tzabcan.
| Species | Sample ID | Locality | LD50 |
Crotoxin homologs |
|
|---|---|---|---|---|---|
| (μg/g mouse) | Detectiona | % ± SD | |||
| C. simus | IBt 226 | La Tinaja, Veracruz | 0.18 (0.15–0.21) | + | 38.5 ± 0.7 |
| IBt270 | Actopan, Veracruz | 0.20 (0.18–0.21) | + | 21.6 ± 0.73 | |
| IBt267 | Puente Nacional, Veracruz | 0.21 (0.20–0.21) | + | 26.3 ± 0.88 | |
| IBt 176 | Santo Domingo, Oaxaca | 0.20 (0.20–0.21) | + | 14.5 ± 0.4 | |
| IBt 268 | Actopan, Veracruz | 0.26 (0.15–0.27) | + | 26.2 ± 0.4 | |
| IBt 225 | Tinajas, Veracruz | 0.26 (0.26–0.26) | + | 44.3 ± 0.24 | |
| IBt 085 | Chiapa de Corzo, Chiapas | 0.26 (0.21–0.30) | + | 7.6 ± 0.5 | |
| IBt 084 | Chiapa de Corzo, Chiapas | 0.30 (0.26–0.32) | + | 6.3 ± 0.42 | |
| IBt 065 | Copainalá, Chiapas | 0.31 (0.30–0.31) | + | 8.4 ± 0.8 | |
| IBt 224 | Playas del Conchal, Veracruz | 0.32 (0.31–0.32) | + | 39.7 ± 0.8 | |
| IBt 066 | Chiapa de Corzo, Chiapas | 0.65 (0.61–0.67) | + | 13.7 ± 0.4 | |
| C. tzabcan | IBt 212 | Solidaridad, Quintana Roo | 0.80 (0.71–0.91) | + | 7.7 ± 0.45 |
| IBt 218 | Chetumal, Quintana Roo | 0.91 (0.89–0.93) | + | 4.4 ± 0.34 | |
| IBt 217 | Chetumal, Quintana Roo | 1.08 (0.96–1.20) | + | 3.0 ± 0.16 | |
| IBt 211 | Solidaridad, Quintana Roo | 1.19 (1.08–1.31) | + | 4.6 ± 0.74 | |
| IBt 216 | Chetumal, Quintana Roo | 1.79 (1.71–1.87) | + | 5.0 ± 0.43 | |
| IBt 207 | Solidaridad, Quintana Roo | 1.99 (1.84–2.16) | + | 7.3 ± 0.45 | |
| IBt 255 | Mérida, Yucatán | 4.68 (4.42–5.00) | – | 0 | |
| IBt 254 | Mérida, Yucatán | 7.21 (5.29–8.79) | – | 0 | |
| IBt 214 | Solidaridad, Quintana Roo | 7.89 (7.47–8.31) | – | 0 | |
| IBt 253 | Mérida, Yucatán | 8.21 (8.00–8.42) | – | 0 | |
| C. culminatus | IBt 150 | Puente de Ixtla, Morelos | 3.42 (3.37–3.47) | – | 0 |
| IBt 205 | Chilpancingo, Guerrero | 3.47 (3.37–3.63) | – | 0 | |
| IBt 168 | Tepalcingo, Morelos | 7.95 (7.79–8.10) | – | 0 | |
| IBt 133 | Alpuyeca, Morelos | 8.53 (8.42–8.68) | – | 0 | |
| IBt 204 | Tlaltizapán, Morelos | 9.31 (9.10–9.58) | – | 0 | |
| IBt 169 | Tepalcingo, Morelos | 9.84 (9.86–10.0) | – | 0 | |
| Csim2A | Villa de Ayala, Morelos | 15.0 (14.3–15.8) | – | 0 | |
| IBt 203 | Tlaltizapán, Morelos | 15.5 (15.0–16.0) | – | 0 | |
| Csim2B | Villa de Ayala, Morelos | 15.9 (14.7–17.3) | – | 0 | |
a
Detection by slot blot, venoms with presence for crotoxin homologs (+), venoms with absence of crotoxin homologs (−).