Table 2.
Absolute prevalence of systemic drug orders for children in US ambulatory settings (2006–2015)
| Orders per 1000 ambulatory visits (95% confidence intervals) | ||||||
|---|---|---|---|---|---|---|
| Category | Age <1m | Age 1m-<2y | Age 2–5y | Age 6–11y | Age 12–17y | All children |
| Any drug | 64.1 (45.3, 83.0) | 406.1 (380.2, 432.0) | 635.8 (605.3, 666.3) | 731.7 (698.1, 765.3) | 759.1 (722.9, 795.2) | 620.7 (597.2, 644.2) |
| Off-label, overall | 52.0 (35.7, 68.4) | 164.0 (149.3, 178.7) | 218.7 (205.0, 232.5) | 253.7 (238.2, 269.3) | 321.5 (299.9, 343.1) | 236.5 (225.1, 247.8) |
| Off-label by indication | 28.21 (17.5, 39.0) | 112.4 (102.1, 122.8) | 190.0 (177.7, 202.3) | 219.3 (204.8, 233.7) | 268.0 (249.0, 287.0) | 194.6 (185.0, 204.2) |
| Off-label by age | 40.8 (26.1, 55.5) | 61.4 (53.3, 69.6) | 33.5 (28.3, 38.6) | 37.6 (32.7, 42.5) | 51.2 (44.8, 57.7) | 45.9 (42.1, 49.8) |
1
Values based on <30 observations