Table II.
Group | Number of subjects | Sampling time-point | |
---|---|---|---|
Blood | Lung tissue and bronchial mucosa | ||
1 | 8 | Pre-dose, 1.5 h; 4 h post-dose | 4 h post-dose |
2 | 8 | Pre-dose, 1.5 h; 8 h post-dose | 8 h post-dose |
3 | 8 | Pre-dose, 1.5 h; 12 h post-dose | 12 h post-dose |
4 | 8 | Pre-dose, 1.5 h; 24 h post-dose | 24 h post-dose |