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Cytotoxicity of tideglusib to vaginal cells and L. acidophilus.
Cytotoxic effects of tideglusib and N-9 on Lactobacillus acidophilus (A, n = 3) and vaginal cells (B, n = 3). (A) The inhibition (%) on L. acidophilus colonies after treatment with DMSO (17%), 100 × MEC of tideglusib (27%), 100 × MEC of N-9 (82%), commercialized N-9 (100%). (B) Inhibition (%) of the compounds on VK2/E6E7 cell proliferation after incubation for 24 h. **p <.01, ns: p >.05.
