Table I.
Demographic and clinical data of patients with chilblain-like lesions observed at the Pediatric Dermatology Unit of the University of Milan between March 26 and April 26, 2020
| ID | Sex | Age at diagnosis | Residence | Nasopharyngeal swab for SARS-CoV-2 | Cohabitants with systemic symptoms/COVID-19 in the 4 weeks preceding lesion onset | Systemic symptoms | Time between systemic symptoms and onset of lesions (days) | Duration of lesions (days) | Location of lesions | Distribution of lesions | Itching (visual analogue scale) | Local pain (visual analogue scale) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 10 | Milan (province) | No | None | None | Not applicable | 23 | Feet (toes) | Bilateral | 0 | 0 |
| 2 | F | 17 | Milan (city) | Negative | Grandfather died of COVID-19 pneumonia | Fever | 13 | 12 (ongoing) | Hand (fingers) | Unilateral | 2 | 0 |
| 3 | F | 4 | Milan (city) | No | None | Fever | –1 | 3 | Feet (toes, dorsum) | Bilateral | 0 | 0 |
| 4 | M | 12 | Milan (province) | No | None | None | Not applicable | 9 (ongoing) | Feet (toes, soles) | Bilateral | 5 | 0 |
| 5 | F | 11 | Milan (province) | No | Both parents (fever); not tested for SARS-CoV-2 | Fever, coryza, cough, abdominal pain | 1 | 16 (ongoing) | Feet (toes) | Bilateral | 2 | 0 |
| 6 | F | 17 | Milan (province) | No | Two friends affected by COVID-19 (fever, cough) | None | Not applicable | 18 (ongoing) | Feet (soles) | Bilateral | 5 | 0 |
| 7 | M | 6 | Milan (province) | No | None | None | Not applicable | 10 (ongoing) | Hands (palms), feet (soles) | Bilateral | 6 | 0 |
| 8 | M | 17 | Milan (province) | No | None | None | Not applicable | 25 (ongoing) | Feet (toes) | Bilateral | 0 | 3 |
| 9 | M | 16 | Milan (province) | No | None | None | Not applicable | 24 (ongoing) | Feet (toes) | Bilateral | 0 | 4 |
| 10∗ | F | 11 | Milan (province) | Negative | Mother (cough); tested negative for COVID-19 | Fever, headache | 1 | 32 (ongoing) | Feet (soles, dorsum) | Bilateral | 1 | 0 |
| 11 | F | 11 | Milan (province) | No | None | Cough, dyspnea | 30 | 18 (ongoing) | Feet (toes) | Bilateral | 0 | 0 |
| 12 | M | 17 | Milan (province) | No | None | None | Not applicable | 24 (ongoing) | Feet (dorsum) | Bilateral | 0 | 2 |
| 13 | M | 11 | Milan (city) | No | None | None | Not applicable | 39 (ongoing) | Foot (toes) | Unilateral | 0 | 0 |
| 14 | F | 13 | Milan (province) | No | Father (fever, cough); not tested for SARS-CoV-2 | None | Not applicable | 13 (ongoing) | Feet (toes) | Bilateral | 0 | 0 |
| 15 | M | 10 | Milan (province) | No | None | None | Not applicable | 21 (ongoing) | Foot (toe) | Unilateral | 0 | 0 |
| 16 | M | 14 | Milan (province) | No | None | Coryza, weakness | 2 | 17 (ongoing) | Foot (sole) | Unilateral | 0 | 0 |
| 17 | M | 11 | Milan (province) | No | None | None | Not applicable | 1 | Ankles | Bilateral | 0 | 0 |
| 18 | M | 2 | Milan (province) | No | Mother (cough and coryza); not tested for SARS-CoV-2 | Cough, coryza | 5 | 5 | Hands (palms) | Bilateral | 0 | 0 |
| 19 | M | 4 | Milan (province) | No | None | None | Not applicable | 7 | Feet (soles) | Bilateral | 0 | 0 |
| 20∗ | F | 11 | Milan (city) | Negative | Both parents (cough); father tested negative for SARS-CoV-2 | Fever, cough | 6 | 19 | Feet (toes, dorsum) | Bilateral | 2 | 0 |
| 21∗ | F | 6 | Milan (province) | Negative | Mother (fever); tested negative for SARS-CoV-2 | Fever | 10 | 7 | Feet (toes, soles) | Bilateral | 0 | 3 |
| 22∗ | M | 5 | Milan (city) | Negative | Grandfather with bilateral pneumonia (not tested for SARS-CoV-2); mother tested negative for SARS-CoV-2 | Cough, dyspnea | 35 | 24 | Feet (toes, soles), hand (palm) | Bilateral | 1 | 5 |
| 23 | F | 6 | Milan (city) | No | None | None | Not applicable | 14 (ongoing) | Feet (toes, soles) | Bilateral | 0 | 0 |
| 24 | M | 14 | Milan (city) | Negative | None | None | Not applicable | 19 (ongoing) | Feet (toes) | Bilateral | 5 | 0 |
| 25 | M | 4 | Milan (province) | No | Mother with COVID-19 (presenting with fever and cough) | Fever, pharyngodynia | 2 | 8 (ongoing) | Ankles | Bilateral | 3 | 0 |
| 26 | M | 14 | Milan (province) | No | Father (fever, cough, dyspnea); not tested for SARS-CoV-2 | None | Not applicable | 24 (ongoing) | Feet (toes) | Bilateral | 0 | 0 |
| 27 | M | 13 | Milan (province) | No | None | None | Not applicable | 6 (ongoing) | Feet (toes, soles) | Bilateral | 4 | 0 |
| 28 | M | 16 | Milan (province) | No | Sister (fever); not tested for SARS-CoV-2 | Fever | 21 | 9 (ongoing) | Feet (toes) | Bilateral | 5 | 0 |
| 29 | F | 10 | Milan (province) | No | None | Fever, cough, weakness, pharyngodynia | 30 | 20 (ongoing) | Feet (toes) | Bilateral | 5 | 0 |
| 30 | F | 14 | Milan (province) | No | Sister (fever, cough, pharyngodynia, weakness) | None | Not applicable | 3 | Feet (toes) | Bilateral | 5 | 0 |
COVID-19, Coronavirus disease 2019; F, female patient; ID, identification; M, male patient; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
∗
Described in a previous article (Colonna C et al. Chilblain-like lesions in children following suspected COVID-19 infection. Pediatr Dermatol. 2020;37(3):437-440).