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Summary of effects of AA/EPA on various indices studied in glioma cells in vitro
| Fatty acid | Parameter | LN229 | HNGC2 |
|---|---|---|---|
| AA | Cell proliferation | ↓↓↓ | ↓↓ |
| EPA | ↔ | ↓↓ | |
| AA | Bcl-2/Bax | ↓↓↓ | ↓↓ |
| EPA | ↓↓ | ↓ | |
| AA | NF-κB/IκB | ↓↓ | ↓↓ |
| EPA | ↓↓↓ | ↓↓↓ | |
| AA | Cytochrome C | ↑↑ | ↑↑ |
| EPA | ↑↑ | ↑↑ | |
| AA | Caspases 3 and 9 | ↑↑ | ↑↑ |
| EPA | ↑↑ | ↑↑ | |
| AA | P53 | ↓↓↓ | ↓↓ |
| EPA | ↓↓ | ↓↓ | |
| AA | Ras | ↓↓↓ | ↑↑ |
| EPA | ↓ | ↔ | |
| AA | MYC | ↓↓↓ | ↓↓↓ |
| EPA | ↓↓ | ↓↓↓ | |
| AA | FOS | ↑ | ↑↑ |
| EPA | ↑↑ | ↓ | |
| AA | COX-1 | ↓ | ↔ |
| EPA | ↔ | ↔ | |
| AA | COX-2 | ↑↑ | ↑↑ |
| EPA | ↑↑↑ | ↑↑ | |
| AA | 5-LOX | ↓ | ↔ |
| EPA | ↓↓ | ↓↓ |
