Table II.
Descriptive statistics for the analysed variables as divided into examined groups
| Variable | All subjects (n = 104) Mean ± SD |
ED-I (n = 34) Mean ± SD |
rDE (n = 70) Mean ± SD |
ED-I vs. rDE | |
|---|---|---|---|---|---|
| Hypochondria scale (Hd) | High scores mean: unspecified physical problems, concern for own health, concentration on unreal somatic problems, energy deficiency, lack of satisfaction, problems with sleep, complaining, claiming attitude | 71.81 ±12.86 | 67.01 ±11.52 | 74.11 ±12.91 | 0.012* |
| Depression scale (D) | High scores mean: depressive mood, low self-esteem and the feeling of being inappropriate, worrying, lack of satisfaction with life status, withdrawal | 77.31 ±11.39 | 73.15 ±10.13 | 79.29 ±11.49 | 0.011* |
| Hysteria scale (Hy) | High scores mean: poor insight into life-related problems and emotions, various somatic fears, problems with sleep, negation, claiming attitude, self-concentration | 71.35 ±12.76 | 65.84 ±12.37 | 73.98 ±12.18 | 0.001* |
| MnSOD mRNA (2–ΔΔct) | 0.537 ±0.17 | 0.514 ±0.21 | 0.547 ±0.15 | 0.796 | |
| MnSOD protein [pg/ml] | 170.57 ±63.25 | 166.23 ±76.36 | 172.35 ±57.38 | 0.731 | |
| MPO mRNA (2–ΔΔct) | 0.319 ±0.04 | 0.321 ±0.04 | 0.318 ±0.04 | 0.844 | |
| MPO protein [ng/ml] | 313.32 ±40.49 | 315.71 ±33.78 | 312.33 ±43.23 | 0.834 | |
| COX-2 mRNA (2–ΔΔct) | 0.237 ±0.04 | 0.241 ±0.03 | 0.235 ±0.04 | 0.409 | |
| COX-2 protein [ng/ml] | 113.69 ±21.56 | 116.47 ±20.67 | 112.55 ±22.01 | 0.491 | |
| iNOS mRNA (2–ΔΔct) | 0.102 ±0.02 | 0.11 ±0.02 | 0.10 ±0.02 | 0.623 | |
| iNOS protein [ng/ml] | 20.73 ±8.51 | 21.85 ±9.49 | 20.27 ±8.13 | 0.749 | |
| MMP-2 mRNA (2–ΔΔct) | 284.27 ±9.35 | 287.16 ±9.34 | 282.97 ±9.13 | 0.039* | |
| MMP-2 protein [ng/ml] | 363.51 ±20.52 | 364.87 ±22.28 | 358.48 ±21.51 | 0.133 | |
| MMP-9 mRNA (2–ΔΔct) | 291.96 ±11.02 | 293.55 ±12.01 | 291.25 ±10.56 | 0.423 | |
| MMP-9 protein [ng/ml] | 360.46 ±21.84 | 364.87 ±22.28 | 358.48 ±21.51 | 0.186 | |
ED-I – first depressive episode, rDE – recurrent depressive episodes, SD – standard deviation,*p statistically significant, MnSOD – manganese superoxide dismutase, MPO – myeloperoxidase, COX-2 – cyclooxygenase 2, iNOS – inducible nitric oxide synthase, MMP-2 – metalloproteinase 2, MMP-9 – metalloproteinase 9.