Table III.
Results of Spearman’s rank correlation for the variables analysed
| Variable | All subjects (N = 104) | ED-I (N = 34) | rDE (N = 70) | ||||
|---|---|---|---|---|---|---|---|
| R Spearman | P-value | R Spearman | P-value | R Spearman | P-value | ||
| MnSOD mRNA (2–ΔΔct) | & Hypochondria | –0.226 | 0.056 | –0.022 | 0.923 | –0.311 | 0.026* |
| & Depression | –0.207 | 0.082 | –0.033 | 0.887 | –0.310 | 0.027* | |
| & Hysteria | –0.162 | 0.175 | –0.082 | 0.725 | –0.264 | 0.062 | |
| MnSOD protein [pg/ml] | & Hypochondria | –0.229 | 0.053 | –0.024 | 0.916 | –0.324 | 0.020* |
| & Depression | –0.168 | 0.159 | –0.001 | 0.996 | –0.257 | 0.068 | |
| & Hysteria | –0.151 | 0.204 | –0.063 | 0.787 | –0.257 | 0.069 | |
| MPO mRNA (2–ΔΔct) | & Hypochondria | 0.222 | 0.060 | 0.188 | 0.414 | 0.257 | 0.068 |
| & Depression | 0.136 | 0.254 | 0.189 | 0.412 | 0.131 | 0.359 | |
| & Hysteria | 0.220 | 0.064 | 0.104 | 0.655 | 0.255 | 0.071 | |
| MPO protein [ng/ml] | & Hypochondria | 0.245 | 0.038* | 0.203 | 0.377 | 0.284 | 0.044* |
| & Depression | 0.155 | 0.193 | 0.226 | 0.325 | 0.153 | 0.285 | |
| & Hysteria | 0.233 | 0.049 | 0.109 | 0.639 | 0.276 | 0.049* | |
| COX-2 mRNA (2–ΔΔct) | & Hypochondria | 0.013 | 0.913 | 0.101 | 0.663 | 0.096 | 0.502 |
| & Depression | 0.116 | 0.334 | 0.407 | 0.067 | 0.089 | 0.536 | |
| & Hysteria | 0.006 | 0.959 | –0.024 | 0.917 | 0.036 | 0.804 | |
| COX-2 protein [ng/ml] | & Hypochondria | 0.050 | 0.675 | 0.033 | 0.887 | 0.103 | 0.470 |
| & Depression | 0.152 | 0.203 | 0.432 | 0.051 | 0.113 | 0.429 | |
| & Hysteria | 0.051 | 0.672 | 0.088 | 0.703 | 0.059 | 0.681 | |
| iNOS mRNA (2–ΔΔct) | & Hypochondria | 0.139 | 0.244 | 0.247 | 0.281 | 0.106 | 0.460 |
| & Depression | 0.013 | 0.911 | 0.006 | 0.980 | 0.023 | 0.872 | |
| & Hysteria | 0.129 | 0.279 | 0.347 | 0.123 | 0.052 | 0.717 | |
| iNOS protein [ng/ml] | & Hypochondria | 0.095 | 0.426 | 0.233 | 0.310 | 0.059 | 0.681 |
| & Depression | 0.003 | 0.977 | 0.016 | 0.946 | 0.002 | 0.991 | |
| & Hysteria | 0.104 | 0.384 | 0.349 | 0.122 | –0.025 | 0.861 | |
| MMP-2 mRNA (2–ΔΔct) | & Hypochondria | –0.097 | 0.349 | –0.070 | 0.718 | –0.059 | 0.635 |
| & Depression | –0.128 | 0.217 | –0.040 | 0.837 | –0.064 | 0.612 | |
| & Hysteria | –0.169 | 0.102 | –0.071 | 0.713 | –0.093 | 0.458 | |
| MMP-2 protein [ng/ml] | & Hypochondria | –0.186 | 0.072 | –0.180 | 0.350 | –0.159 | 0.202 |
| & Depression | –0.301 | 0.003* | –0.155 | 0.423 | –0.319 | 0.009* | |
| & Hysteria | –0.228 | 0.027* | –0.319 | 0.092 | –0.131 | 0.294 | |
| MMP-9 mRNA (2–ΔΔct) | & Hypochondria | 0.024 | 0.817 | –0.042 | 0.831 | 0.059 | 0.637 |
| & Depression | –0.150 | 0.146 | –0.137 | 0.479 | –0.142 | 0.254 | |
| & Hysteria | 0.035 | 0.736 | –0.165 | 0.392 | 0.142 | 0.254 | |
| MMP-9 protein [ng/ml] | & Hypochondria | –0.176 | 0.089 | –0.108 | 0.579 | –0.164 | 0.189 |
| & Depression | –0.323 | 0.001* | –0.295 | 0.121 | –0.300 | 0.014* | |
| & Hysteria | –0.122 | 0.237 | –0.076 | 0.693 | –0.077 | 0.538 | |
ED-I – first depressive episode, rDE – recurrent depressive episodes,*p statistically significant, MnSOD – manganese superoxide dismutase, MPO – myeloperoxidase, COX-2 – cyclooxygenase 2, iNOS – inducible nitric oxide synthase, MMP-2 – metalloproteinase 2, MMP-9 – metalloproteinase 9.