Table 2.
Bivariate and multivariable relationship in the GEE between explanatory variables and the outcome of being in the same genetic dyad but not in the same partner notification interview-based sexual network component, by odds ratio (OR) and confidence intervals (CI) [N=76 pairs].
| Network Component |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Characteristics of Genetic Dyads | Total (N=76) | Different (N=49) | Same (N=27) | Bivariable | Multivariable | |||||||
| N | (col %) | N | (row %) | N | (row %) | OR | (95%CI) | P-value | Adjusted OR | (95%CI) | P-value | |
| Race Assortativity | ||||||||||||
| Different race persons in pair | 18 | (24) | 13 | (72) | 5 | (28) | 1.6 | (0.5-5.1) | 0.43 | |||
| Both persons identify as the same race | 53 | (76) | 36 | (62) | 22 | (38) | ref | |||||
| Black Race in Dyad | ||||||||||||
| Neither person African-American race | 17 | (22) | 13 | (76) | 4 | (24) | 2.1 | (0.6-7.2) | 0.25 | |||
| At least one person identifies as Black | 59 | (78) | 36 | (61) | 23 | (39) | ref | |||||
| Gender in Dyad | ||||||||||||
| Male-male pair | 66 | (87) | 46 | (70) | 20 | (30) | 5.3 | (1.3-22.9) | 0.02* | 16.7** | (1.8-159.2) | 0.01 |
| Male/female or female/female pair | 10 | (13) | 3 | (30) | 7 | (70) | ref | ref | ||||
| Age at HIV Diagnosis | ||||||||||||
| Both age 30 or younger at diagnosis | 44 | (58) | 31 | (70) | 13 | (30) | 1.9 | (0.7-4.8) | 0.20 | |||
| At least one person >30 years of age | 32 | (42) | 18 | (56) | 14 | (44) | ref | |||||
| Age Difference | ||||||||||||
| > 5 years | 36 | (47) | 25 | (69) | 11 | (31) | 1.5 | (0.6-3.9) | 0.39 | |||
| ≤ 5 years of age | 40 | (53) | 24 | (60) | 16 | (40) | ref | |||||
| Wake County Residence in Dyad | ||||||||||||
| Both resided in Wake County at diagnosis | 49 | (64) | 32 | (65) | 17 | (35) | 1.1 | (0.4-2.9) | 0.84 | |||
| At least one person not a Wake resident | 27 | (36) | 17 | (63) | 10 | (37) | ref | |||||
| Time Between HIV Diagnoses in Dyad | ||||||||||||
| < 5 years | 62 | (82) | 42 | (68) | 20 | (32) | 2.1 | (0.6-6.8) | 0.22 | |||
| ≥ 5 years between HIV diagnoses | 14 | (18) | 7 | (50) | 7 | (50) | ref | |||||
| Interview of Person Diagnosed Later in Time | ||||||||||||
| Partners not disclosed | 17 | (22) | 14 | (82) | 3 | (18) | 3.2 | (0.8-12.4) | 0.09* | 4.9 | (0.5-44.6) | 0.16 |
| Partner elicitation completed | 59 | (78) | 35 | (59) | 24 | (41) | ref | ref | ||||
| Acute HIV Infection at Diagnosis in Dyad | ||||||||||||
| Neither acutely infected at diagnosis | 67 | (88) | 45 | (67) | 22 | (33) | 2.6 | (0.6-10.5) | 0.19* | 4.5** | (1.8-11.0) | <0.01 |
| At least one person acutely infected | 9 | (12) | 4 | (44) | 5 | (56) | ref | ref | ||||
| Genetic Distance (per 1% increase) | 0.76 +/− 0.52 | 0.89 +/− 0.48 | 0.52 +/− 0.50 | 4.9 | (1.6-14.8) | <0.01* | 8.3** | (2.4-28.5) | <0.01 | |||
| Anonymous Partners among Dyad | ||||||||||||
| Either member had ≥1 anonymous partner | 35 | (73) | 27 | (77) | 8 | (23) | 1.5 | (0.4-6.2) | 0.56 | |||
| Neither had anonymous partners | 13 | (27) | 9 | (69) | 4 | (31) | ref | |||||
| Behavioral Assortativity (total sex partners) | ||||||||||||
| Fewer than 10 sex partners difference | 66 | (87) | 44 | (67) | 22 | (33) | 2.0 | (0.5-7.6) | 0.31 | |||
| ≥ 10 sex partners difference among pair | 10 | (13) | 5 | (50) | 5 | (50) | ref | |||||
*
Tested in the multivariable GEE based upon bivariate relationship with outcome
**
Significant in the multivariable GEE at alpha=0.05