Figure 5.

Antibody-mediated responses to Plasmodium falciparum in high- and low-exposure groups. A, The sero-high group had significantly higher (P = .006) titers of antibodies to sporozoite antigens, expressed as arbitrary units (AU). B, There were no significant differences between groups in their ability to block sporozoite invasion of HC04 hepatocytes. C, Plasma from the sero-high group also had significantly higher (P = .0003) levels of antibodies to asexual-stage antigens, also expressed as AU. D, Purified immunoglobulin G from the sero-high exposure group also had significantly higher growth inhibitory activity (P = .025) against blood-stage 3D7 parasites.