Table 2.
Zika Virus (ZIKV)–Exposed Infant Group and Trimester of ZIKV Infection
| Trimester of ZIKV Infectiona | |||||
|---|---|---|---|---|---|
| Infant Group | Infants with Laboratory-Confirmed ZIKV | First | Second | Third | P Valueb,c |
| Neither SGA nor microcephaly, N = 115 | 27 (56.3%) | 58 (85.3%) | 30 (93.8%) | ||
| Yes | 16 (59.3%) | 14(24.1%) | 8 (26.7%) | .004 | |
| No | 11 (40.7%) | 44(75.9%) | 22 (73.3%) | ||
| Proportional microcephaly, N = 8 | 8 (16.7%) | 0 (0%) | 0 (0%) | ||
| Yes | 5 (62.5%) | 0 (0%) | 0 (0%) | .231 | |
| No | 3 (37.5%) | 0 (0%) | 0 (0%) | ||
| Disproportional microcephaly, N = 12 | 10 (20.8%) | 2 (2.9%) | 0 (0%) | ||
| Yes | 6 (60.0%) | 0 (0%) | 0 (0%) | .315 | |
| No | 4 (40.0%) | 2 (100%) | 0 (0%) | ||
| SGA, N = 13 | 3 (6.3%) | 8 (11.8%) | 2 (6.3%) | ||
| Yes | 2 (66.7%) | 4 (50.0%) | 1 (50.0%) | >.999 | |
| No | 1 (33.3%) | 4 (50.0%) | 1 (50.0%) | ||
| Total | 48 | 68 | 32 | ||
| Yes | 29 (60.4%) | 18 (26.5%) | 9 (28.1%) | ||
| No | 19 (39.6%) | 50 (73.5%) | 23 (71.9%) | <.001 | |
Abbreviations: SGA, small for gestational age; ZIKA, Zika virus.
aTrimester of infection was unknown for 8 infants
bFisher exact test examining association between laboratory-confirmed ZIKV and trimester of infection within each infant group.
cFischer exact test was used to determine P value.