Table 2.
Serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyltransferase (GGT), and total bilirubin
Variable | Desflurane group (n=81) | Sevoflurane group (n=81) | P |
---|---|---|---|
Aspartate aminotransferase (U/L) | |||
T0 | 257.43±89.14 | 248.12±85.37 | 0.498 |
T1 | 164.15±30.70 | 201.92±41.37 | 0.001* |
T2 | 103.54±19.40 | 159.11±29.80 | 0.001* |
T3 | 72.34±10.25 | 111.56±17.59 | 0.001* |
T4 | 55.20±8.04 | 79.40±11.38 | 0.001* |
T5 | 32.70±7.25 | 45.20±9.34 | 0.001* |
T6 | 25.70±5.40 | 29.38±7.50 | 0.001* |
T7 | 23.90±4.51 | 25.11±5.50 | 0.127 |
Alanine aminotransferase (U/L) | |||
T0 | 235.22±66.45 | 227.63±58.70 | 0.442 |
T1 | 180.35±44.80 | 198.56±56.68 | 0.024* |
T2 | 157.43±33.72 | 170.18±42.08 | 0.034* |
T3 | 129.10±22.60 | 140.32±37.70 | 0.020* |
T4 | 98.99±10.43 | 107.39±21.30 | 0.002* |
T5 | 67.15±9.90 | 80.25±13.40 | 0.006* |
T6 | 44.52±7.18 | 52.76±10.03 | 0.001* |
T7 | 26.26±6.30 | 28.10±8.70 | 0.125 |
Alkaline phosphatase (U/L) | |||
T0 | 182.65±16.73 | 179.15±15.36 | 0.167 |
T1 | 172.90±10.43 | 175.27±12.50 | 0.192 |
T2 | 162.80±8.50 | 164.45±9.30 | 0.082 |
T3 | 152.40±7.10 | 153.28±7.34 | 0.439 |
T4 | 143.50±6.28 | 145.10±5.05 | 0.075 |
T5 | 134.95±4.85 | 136.40±5.90 | 0.089 |
T6 | 124.70±4.14 | 125.86±±4.60 | 0.093 |
T7 | 121.80±4.90 | 122.63±5.60 | 0.317 |
Gamma-glutamyltransferase (U/L) | |||
T0 | 82.54±7.13 | 81.59±6.80 | 0.386 |
T1 | 75.30±6.50 | 75.40±6.13 | 0.919 |
T2 | 68.90±5.20 | 70.12±5.70 | 0.156 |
T3 | 63.96±4.90 | 65.19±5.10 | 0.119 |
T4 | 58.80±4.47 | 60.13±5.23 | 0.083 |
T5 | 52.40±4.52 | 53.25±4.75 | 0.245 |
T6 | 50.21±5.47 | 51.29±5.63 | 0.217 |
T7 | 47.80±4.60 | 48.11±5.52 | 0.698 |
Bilirubin (µmol/L) | |||
T0 | 42.18±6.40 | 43.46±7.30 | 0.237 |
T1 | 38.24±6.38 | 40.04±6.55 | 0.078 |
T2 | 35.77±5.90 | 37.20±6.10 | 0.131 |
T3 | 31.20±7.50 | 33.04±6.36 | 0.094 |
T4 | 28.80±7.41 | 30.14±7.11 | 0.155 |
T5 | 23.96±6.30 | 26.01±7.92 | 0.069 |
T6 | 21.60±6.19 | 23.20±7.16 | 0.130 |
T7 | 16.84±5.33 | 18.53±6.40 | 0.165 |
*P<0.05 significant comparison between the two groups. T0 – at the preoperative period, T1 – Directly after surgery, T2 – 1st postoperative day, T3 – 2nd postoperative day, T4 – 3rd postoperative day, T5 – 5th postoperative day, T6 – 7th postoperative day, T7 – 10th postoperative day