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. 2020 May 1;64(5):383–390. doi: 10.4103/ija.IJA_168_20

Table 4.

Intraoperative data and outcome of patients

Variable Desflurane group (n=81) Sevoflurane group (n=81) P
Duration of procedure (min) 49.27±5.75 47.94±4.80 0.112
Duration of anesthesia (min) 60.30±13.40 66.59±17.84 0.012*
Temperature (°C) 36.30±0.50 36.20±0.48 0.196
End-tidal CO2 (mmHg) 35.86±2.28 36.17±2.40 0.400
Total fentanyl dose (µg) 136.25±27.80 130.90±23.63 0.188
Total atracurium dose (mg) 57.35±12.80 54.79±10.75 0.170
End-tidal concentration (%) 5.32±0.31 2.42±0.24 0.001*
Ephedrine
 Number of patients 9 (11.11%) 17 (20.98%) 0.054
 Dose (mg) 6.85±2.57 7.15±3.45 0.531
Atropine
 Number of patients 5 (6.7%) 13 (16.04%) 0.077
 Dose (mg) 0.58±0.18 0.61±0.20 0.317
Hypotension (SAP ≤20% below baseline) 9 (11.11%) 17 (20.98%) 0.054
Hypertension (SAP ≥20% above baseline) 16 (19.95%) 9 (11.11%) 0.191
Bradycardia (HR <60 bpm) 5 (6.7%) 13 (16.04%) 0.077
Tachycardia (HR >100 bpm) 14 (17.28%) 9 (11.11%) 0.368
Emergence cough 9 (11.11%) 6 (7.40%) 0.587
Emergence time (min) 10.53±4.62 12.48±5.84 0.019*
Extubation time (min) 7.87±3.37 9.18±3.90 0.023*
Emergence agitation - -
Incidence of nausea and vomiting 23 (28.39%) 39 (48.14%) 0.015*
Intraoperative fluids [only crystalloids] (mL) 1873.30±314.80 1840.90±324.10 0.519
Intraoperative blood loss (mL) 73.15±10.54 70.75±9.71 0.133
Hematocrit (%) 35.54±2.15 36.00±2.23 0.183
Renal functions tests
 Serum creatinine (mg/dL) 1.12±0.3 1.17±0.21 0.220
 Blood urea nitrogen (mg/dL) 7.98±2.43 8.10±2.31 0.747
Hospital length of stay (days) 4.60±1.15 5.05±±1.10 0.011*
Postoperative morbidity or mortality - -

*P<0.05 significant comparison between the two groups. SAP – Systolic arterial blood pressure, HR – Heart rate. Data are presented as mean±SD, number, %