Table 4.
Intraoperative data and outcome of patients
Variable | Desflurane group (n=81) | Sevoflurane group (n=81) | P |
---|---|---|---|
Duration of procedure (min) | 49.27±5.75 | 47.94±4.80 | 0.112 |
Duration of anesthesia (min) | 60.30±13.40 | 66.59±17.84 | 0.012* |
Temperature (°C) | 36.30±0.50 | 36.20±0.48 | 0.196 |
End-tidal CO2 (mmHg) | 35.86±2.28 | 36.17±2.40 | 0.400 |
Total fentanyl dose (µg) | 136.25±27.80 | 130.90±23.63 | 0.188 |
Total atracurium dose (mg) | 57.35±12.80 | 54.79±10.75 | 0.170 |
End-tidal concentration (%) | 5.32±0.31 | 2.42±0.24 | 0.001* |
Ephedrine | |||
Number of patients | 9 (11.11%) | 17 (20.98%) | 0.054 |
Dose (mg) | 6.85±2.57 | 7.15±3.45 | 0.531 |
Atropine | |||
Number of patients | 5 (6.7%) | 13 (16.04%) | 0.077 |
Dose (mg) | 0.58±0.18 | 0.61±0.20 | 0.317 |
Hypotension (SAP ≤20% below baseline) | 9 (11.11%) | 17 (20.98%) | 0.054 |
Hypertension (SAP ≥20% above baseline) | 16 (19.95%) | 9 (11.11%) | 0.191 |
Bradycardia (HR <60 bpm) | 5 (6.7%) | 13 (16.04%) | 0.077 |
Tachycardia (HR >100 bpm) | 14 (17.28%) | 9 (11.11%) | 0.368 |
Emergence cough | 9 (11.11%) | 6 (7.40%) | 0.587 |
Emergence time (min) | 10.53±4.62 | 12.48±5.84 | 0.019* |
Extubation time (min) | 7.87±3.37 | 9.18±3.90 | 0.023* |
Emergence agitation | - | - | |
Incidence of nausea and vomiting | 23 (28.39%) | 39 (48.14%) | 0.015* |
Intraoperative fluids [only crystalloids] (mL) | 1873.30±314.80 | 1840.90±324.10 | 0.519 |
Intraoperative blood loss (mL) | 73.15±10.54 | 70.75±9.71 | 0.133 |
Hematocrit (%) | 35.54±2.15 | 36.00±2.23 | 0.183 |
Renal functions tests | |||
Serum creatinine (mg/dL) | 1.12±0.3 | 1.17±0.21 | 0.220 |
Blood urea nitrogen (mg/dL) | 7.98±2.43 | 8.10±2.31 | 0.747 |
Hospital length of stay (days) | 4.60±1.15 | 5.05±±1.10 | 0.011* |
Postoperative morbidity or mortality | - | - |
*P<0.05 significant comparison between the two groups. SAP – Systolic arterial blood pressure, HR – Heart rate. Data are presented as mean±SD, number, %