Table 1. Clinical scoring of animals.
Disease score | Clinical symptoms of EAE |
---|---|
0 | No clinical signs of EAE |
1 | Limp tail |
2 | Paresis of one or two hind limbs |
3 | Unilateral hind leg paralysis |
4 | Bilateral hind leg paralysis |
5 | Bilateral hind leg paralysis and incontinence or moribund |
Clinical assessment of animals induced with experimental autoimmune encephalomyelitis (EAE).