Figure 4.
Treatment protocol for the gene therapy study utilized in the Bluebird Starbeam ALD-102 trial. Abbreviations: ALDP, adrenoleukodystrophy protein; DP, drug product; HSC, hematopoietic stem cell; LTF, long-term follow-up. (Reproduced with permission from Sevin, C. Phase 2/3 trial to assess the safety and efficacy of lenti-D hematopoietic stem cell gene therapy for cerebral adrenoleukodystrophy. Presented at: European Society of Paediatric Neurology, Megaron Athens International Conference Centre, Athens, Greece, September 2019. Oral Abstract Presentation [Abstract OC036]).