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Acvr2b expression in gonadotropes is required for quantitatively normal FSH production in male, but not female, mice. Serum FSH levels in control and Acvr2b cKO (cKO-B) (A) males and (C) females. Serum LH levels in control and cKO-B (B) males and (D) females. Pituitary Fshb, Lhb, Cga, and Gnrhr mRNA levels assessed by RT-qPCR in (E) male and (F) female control and cKO-B mice. Rpl19 was used as the housekeeping gene. t-tests were used for statistical analyses, *P < 0.05, ***P < 0.001.
