Figure 8.

FSH, but not LH production is impaired in gonadectomized dcKO females. (A) Serum FSH and (B) LH in sham-operated (Sham) or ovariectomized (OVX) control and dcKO females. (C-F) Pituitary Fshb, Lhb, Cga, and Gnrhr mRNA levels assessed by RT-qPCR in female Sham or OVX control and dcKO mice. Rpl19 was used for normalization in all RT-qPCR experiments. Two-way ANOVAs, followed by Holm-Sidak multiple comparison post-hoc tests, were used for statistical analyses, *P < 0.05, **P < 0.01, ***P < 0.001.