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. 2020 Jun 10;6(24):eaay8299. doi: 10.1126/sciadv.aay8299

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Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 2 — Within each tissue, the length of the ERs Mb overlapping (A) all annotation features, (B) purely exons, (C) exons and introns, (D) exons and intergenic regions, (E) purely intergenic regions, and (F) purely introns according to Ensembl v92 was computed. Tissues are plotted in descending order based on the respective total size of intronic and intergenic regions. Tissues are color-coded as indicated in the x axis, with GTEx brain regions highlighted with bold font. At least 8.4 Mb of previously unannotated transcription was discovered in each tissue, with the greatest quantity found within brain tissues (mean across brain tissues, 18.6 Mb; nonbrain, 11.2 Mb; two-sided Wilcoxon rank sum test, P = 2.35 × 10⁻¹⁰.