TABLE V.
List of amino acids with the largest values of LR subgraph centrality in the average free protease (average of 6M03, 6Y2E, 6M2Q) and with the same parameter for the protease bounded to inhibitors (6M0K, 6LZE, and 6Y2G). The amino acids in the bounded protease that are not in the top rank of the free one are marked in bold.
| Rank | Average | 6M0K | 6LZE | 6Y2G |
|---|---|---|---|---|
| 1 | N28 | N28 | N28 | N28 |
| 2 | G29 | G29 | G29 | G29 |
| 3 | L27 | L27 | L27 | Q19 |
| 4 | V18 | V18 | Q19 | V18 |
| 5 | Q19 | Q19 | V18 | L27 |
| 6 | V20 | V20 | V20 | V20 |
| 7 | G146 | G120 | G146 | G146 |
| 8 | G120 | G146 | S144 | C38 |
| 9 | L30 | L30 | C38 | M17 |
| 10 | C38 | C38 | N119 | S144 |
| 11 | M17 | M17 | C117 | W31 |
| 12 | N119 | S144 | G120 | G120 |
| 13 | S144 | N119 | Y118 | S147 |
| 14 | Y118 | Y118 | M17 | L30 |
| 15 | C117 | C117 | S147 | Y37 |
| 16 | W31 | W31 | W31 | C117 |
| 17 | V36 | V36 | V36 | V36 |
| 18 | Y37 | Y37 | L30 | V68 |
| 19 | S147 | S147 | Y37 | N119 |
| 20 | T26 | C145 | T21 | C145 |
| 21 | C145 | V68 | C145 | T21 |
| 22 | T21 | T21 | T26 | Q69 |