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. 2020 Jun 10;40(6):BSR20200286. doi: 10.1042/BSR20200286

Table 2. Clusters of CHD genes’ PPI network.

Cluster Score Nodes Edges Genes
1 44.28 51 1107 ELN, VEGFA, THBS1, IL1B, PPARG, LEP, PECAM1, AGT, ICAM1, KDR, TIMP1, ESR1, MMP9, IL10, MMP2, IL18, CXCL12, CCL2, IGF1, TGFB1, FGF2, CAT, VCAM1, CXCL8, MMP1, IL2, APOE, HMOX1, IFNG, CRP, NOS3, PTGS2, ADIPOQ, IL1A, ACE, SERPINE1, SELP, INS, IL6, EDN1, TLR4, VWF, SELE, RETN, TNF, ALB, MPO, TNFRSF1A, MMP3, FN1, PLG
2 13.394 34 221 APOA1, PLTP, APOB, F2R, LPL, APOC3, ABCG8, F8, CETP, MMP8, F2, LIPC, CYP7A1, APOA5, APOC1, SAA4, LIPG, CDKN2A, PLA2G7, PROC, LCAT, CST3, APOA4, TF, IRS1, SERPINC1, PPBP, AR, NPC1L1, ABCG5, APOC2, PCSK9, F13A1, GGT1
3 5.917 25 71 GNB3, ADORA1, CALCA, LDLR, PPARA, PON1, ITGA2B, COG2, APOA2, P2RY12, PTGS1, LPA, HMGCR, LIPE, ITGB3, F5, FGF21, GHRL, AGTR2, OLR1, NAMPT, FGA, CLU, FGB, ADM
4 5.091 23 56 GCG, IL6R, CCR2, SOD2, ABCA1, LCN2, HP, C3, MTTP, IL1RN, ELANE, THBD, CCR5, HIF1A, PF4, CD40LG, SCARB1, IGFBP3, IL1R1, KNG1, AGTR1, PLAT, GPT
5 4.5 5 9 PSRC1, BUD13, ZPR1, SORT1, CELSR2
6 3.2 6 8 NPPA, TNNI3, PIK3C2A, NPPB, DNM2, VAMP8
7 3 3 3 CYP2C8, PLA2G2A, CYP2J2
8 3 3 3 CYP2C19, ALDH2, ADH1B
9 2.5 9 10 LEPR, ADRB2, CPB2, NPY, CYP19A1, F7, NOS1, TFPI, SHBG