Table 2.
Baseline patient and tumor characteristics for all patients, those with a recognizable DIL on pathology and those without a DIL. Values are given as median (Inter-Quartile-Range) or number (%) as appropriate.
| Characteristic | All Patients [n = 455] | DIL present [n = 396] | No DIL present [n = 59] | p-value∗ |
|---|---|---|---|---|
| Age [years] | 65.6 (60.3–69.8) | 65.4 (60.1–69.7) | 66.4 (61.2–71.5) | 0.45 |
| Baseline IPSS | 6 (3–11) | 6 (3–10) | 8 (3–14) | 0.12 |
| Initial PSA [ng/mL] |
7.1 (5.4–9.2) |
7.0 (5.4–9.0) |
7.4 (5.8–10.0) |
0.28 |
| T-Stage |
0.09 |
|||
| T1 | 329 (72%) | 282 (71%) | 47 (80%) | |
| T2a | 89 (20%) | 82 (21%) | 7 (12%) | |
| T2b | 28 (6%) | 26 (7%) | 2 (3%) | |
| T2c |
9 (2%) |
6 (2%) |
3 (5%) |
|
| Gleason Grade Group |
0.33 |
|||
| 1 | 77 (17%) | 63 (16%) | 14 (24%) | |
| 2 | 322 (71%) | 283 (71%) | 39 (66%) | |
| 3 | 56 (12%) | 50 (13%) | 6 (10%) | |
| Biopsy Cores Sampled | 11 (10–12) | 10 (10–12) | 12 (10–12) | 0.002 |
| Biopsy Cores Positive |
4 (2–6) |
4 (2–6) |
4 (2–5.5) |
0.84 |
| Biopsy Positive Regions | ||||
| Base Cores Positive | 1 (0–2) | 1 (0–2) | 1 (0–2) | 0.14 |
| Mid Gland Cores Positive | 2 (1–2) | 2 (1–2) | 1 (1–2) | 0.98 |
| Apex Cores Positive | 1 (0–2) | 1 (0–2) | 1 (0–2) | 0.46 |
| Use of ADT | 84 (18%) | 71 (18%) | 13 (22%) | 0.47 |
∗Mann-Whitney-Wilcoxon or Fisher's exact test was used as appropriate between no DIL and DIL groups.