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Aging increased SIRT expression in skeletal muscle. Representative Western blots (a) of the protein levels of SIRT1 (b), SIRT3 (c), SIRT5 (d), SIRT6 (e), and GCN5 (f) in two skeletal muscles and cardiac muscle of young (N = 8), mid-aged (N = 8), and old mouse (N = 8), respectively. Data are mean ± SEM. *P < 0.05, **P < 0.01, Mid-aged or Old vs. Young; †P < 0.05, ††P < 0.01, old vs. mid-aged
