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. 2020 Jun 4;7:90. doi: 10.3389/fcvm.2020.00090

Figure 5.

Figure 5

Angiogram, NIRS, OCT, and histology findings in a patient who died of ventricular rupture 5 days after imaging. The blue line on the angiogram (A1) shows the IVUS-NIRS and OCT pullback location in LAD during stenting at a more distal location. The chemogram (A2) and cross-section IVUS-NIRS (A3) shows lipid from 10 p.m. to 3 p.m. OCT from the same cross-section shows a thick cap of 300 microns, and signs of calcification which complicate the detection of lipid by OCT. In each image, the arrow marks the location of superficial calcium, the hash-tag marks the location of a lipid core underlying the calcification, and the the asterisk marks the location of a lipid pool. Adapted from Zanchin et al. (49). The findings show the complementarity of NIRS and OCT data—NIRS identifies lipid without interference by calcium and OCT shows the thickness of the cap over the lipid. In this case in which the plaque was not causing obstruction, the lipid core would not be expected to be dangerous since a thick cap is present.