TABLE 2.
Metabolite ratios on MRS samplings of HSP patients and control group at baseline.
| R pre-central |
L pre-central |
R pre-frontal |
L pre-frontal |
|||||||||
| Patients | Control | p-value | Patients | Control | p-value | Patients | Control | p-value | Patients | Control | p-value | |
| (n = 31) | (n = 31) | (n = 31) | (n = 31) | (n = 16) | (n = 14) | (n = 16) | (n = 14) | |||||
| NAA/Cr | 1.72 ± 0.21 | 1.74 ± 0.18 | ns | 1.75 ± 0.16 | 1.81 ± 0.15 | ns | 1.70 ± 0.16 | 1.84 ± 0.20 | 0.040 | 1.95 ± 0.29 | 2.09 ± 0.21 | ns |
| Cho/Cr | 0.77 ± 0.13 | 0.70 ± 0.11 | 0.032 | 0.75 ± 0.14 | 0.77 ± 0.12 | ns | 0.74 ± 0.11 | 0.75 ± 0.15 | ns | 0.73 ± 0.11 | 0.78 ± 0.13 | ns |
| myo-Ins/Cr | 0.61 ± 0.24 | 0.56 ± 0.08 | ns | 0.64 ± 0.12 | 0.57 ± 0.09 | 0.018 | 0.66 ± 0.14 | 0.61 ± 0.12 | ns | 0.64 ± 0.16 | 0.62 ± 0.08 | ns |
NAA, N-acetyl-aspartate; Cr, creatine; Cho, choline; myo-Ins, myo-inositol; ns, not significant. Bold characters represent values with p < 0.05.