Table 2.
Treatments and outcome of AIHA patients, altogether and according to PNH positivity.
| All patients | PNH neg | PNH pos | |
|---|---|---|---|
| Treatment and outcome | N = 99 | N = 62 | N = 37 |
| First therapy line N(%) | 96 (96) | 61(98) | 35 (94) |
| Second therapy line N(%) | 57 (57) | 35 (56) | 20 (54) |
| Third therapy line or > N(%) | 31 (31) | 19 (31) | 12 (32) |
| Median RFS days (range) | 539 (25–6,014) | 700 (25–6,014) | 338 (42–3,483) |
| Evans (%) | 14 (14) | 6 (10) | 7 (19) |
| Acute renal failure (%) | 7 (7) | 6 (10) | 1 (3) |
| Infections (%) | 31 (31) | 19 (31) | 10 (29) |
| Thrombosis (%) | 12 (12) | 7 (11) | 5 (14) |
| Death (%) | 8 (8) | 3(5) | 5(14) |
| Median OS m(%) | 25 (0–262) | 26 (0–205) | 24 (2–62) |
OS, overall survival; RFS, relapse free survival.