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. 2020 Jun 10;11:2936. doi: 10.1038/s41467-020-16747-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Comparison of differential RNA expression and changes to RPF abundance of protein-coding RNAs after 2 h (left panel) or 6 h (right panel) of TM treatment. Loci with a P-value below threshold are depicted yellow, plotted are log2-fold changes of mean values. b Analyses of ribosome loading scores of protein-coding RNAs after 2 h (left panel) and 6 h (right panel) of TM stimulation. Note the overall reduction in ribosome loading (for reference the dashed line indicates no change in ribosome loading). RNAs that exhibit statistically significant changes in ribosome loading are shown in yellow.