Table 1.
Demographic characteristics, brain volumes, and values of TNF-α of participants.
| Healthy subjects | MDD patients | ||
|---|---|---|---|
| (n = 38) | (n = 45) | p-value | |
| Age, years; mean, (range, SD) | 43.1 (22–65, 11.3) | 47.2 (20–73, 14.3) | 0.15 |
| Female, numbers | 12 | 22 | 0.12 |
| Body mass index | 21.1 (3.1) | ||
| Education years, mean (SD) | 13.2 (2.3) | ||
| Smokers (%) | 18 (40) | ||
| HAMD-17, mean of total scores (SD) | 22.6 (5.9) | ||
| Inpatients (%) | 30 (67) | ||
| History of suicide attempt (%) | 10 (22) | ||
| ICV, mean (SD) | 1443 (153) ml | 1401 (146) ml | 0.20 |
| TNF-α, mean; pg/mL (SD) | 1.270 (0.365) | 1.602 (0.607) | <0.01 |
SD standard deviation, ICV intracranial volume, MDD major depression disorders, HAMD-17 17-item Hamilton Rating Scale for Depression, TNF tumor necrosis factor.