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. 2020 Jun 10;11:2932. doi: 10.1038/s41467-020-16503-2

Fig. 1. Structure of the human mitochondrial preinitiation translation complex (mtPIC-2).

Fig. 1

a Surface representation of the mtSSU with mtIF3 (orange) and mtIF2 (blue). Empty tRNA-binding sites and mRNA channel are indicated. The binding of mtIF2 is accomplished due to mtIF3 NTD restricting the mtSSU head movement. b Relative positions of mtIF3 colored by domains (NTD purple, linker dark gray, CTD orange, CTE red) and mtIF2.