Table 9.

Top 20 OMIM genes showing the best improvement in genotypability.

OMIM	% Genotypability			% Diff.	%10X Coverage
	S	M	L		S	M	L
RPS26	47.13	100	100	52.87	100	100	100
RPL15	49.98	100	100	50.02	99.90	100	100
RPL21	60.60	100	100	39.4	100	100	100
RPSA	63.29	100	100	36.71	100	100	100
GCSH	64.56	100	97.38	35.44	100	100	100
HNRNPA1	66.84	100	100	33.16	100	100	100
CISD2	53.37	85.15	100	31.78	100	100	100
IFNL3	69.43	100	100	30.57	100	100	100
LEFTY2	74.00	100	100	26.00	100	100	100
BMPR1A	74.19	100	100	25.81	100	100	100
RPS23	75.00	100	100	25.00	100	100	100
ISCA1	75.13	100	100	24.87	100	100	100
ALG10	75.15	100	100	24.85	100	100	100
IFITM3	77.53	100	100	22.47	100	100	100
PTEN	78.55	100	100	21.45	98.49	100	100
BANF1	78.64	100	100	21.36	100	100	100
HLA-A	79.02	100	100	20.98	99.88	100	99.82
RPS28	80.79	100	100	19.21	100	100	100
RP9	78.88	97.60	100	18.72	100	100	100
CYP11B1	81.73	100	100	18.27	100	100	100

Top 20 OMIM genes showing the best improvement in genotypability following the extension of the DNA fragment length from short to medium and short to long (Twist enrichment platform). The data represent the maximum difference in genotypability at 80X mapped coverage on the Twist design. DNA fragment lengths: S = short, M = medium, L = long.