Table 1.
Allostatic load parameters and cut-off points.
| Affected systems | Allostatic Load Parameters | Cut-off points (for AL index) (32) |
|---|---|---|
| Primary mediators | ||
| HPA-Cortisol | Cortisol | >32nM Salivary |
| DHEA (dehydro-epi-androsterone) | <80 ng/ml in men <35 ng/ml in women (plasma) |
|
| Autonomic System | Noradrenaline | >100pg/ml (plasma) |
| MHPG (methoxy-hydroxy-phenylglycol) | >2,750nM (salivary) | |
| Secondary mediators | ||
| Cardiovascular | Systolic blood pressure | >140 mmHg |
| Diastolic blood pressure | >90 mmHg | |
| Metabolism: Lipids and adipose tissue deposition | Body Mass Index | >25 |
| Waist-hip ratio | >1 in men >0.8 in women |
|
| Total cholesterol | >200 mg/dl (plasma) | |
| LDL (low density lipoprotein) | >120 mg/dl (plasma) | |
| HDL (high density lipoprotein) | <37 mg/dl (plasma) | |
| Total cholesterol/HDL ratio | >3.5 mg/dl (plasma) | |
| Metabolism: Glucids, proteins and renal function | Glycated hemoglobin | >6mg/dl (plasma) |
| Creatinine | >1.2mg/dl (plasma) | |
| Albumin | <3.5 g/dl (plasma) | |
| Immune System | C-reactive protein | >7.1mg % (plasma) |
| Fibrinogen | >400mg/dl (plasma) | |