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. 2020 Jun 4;11:518. doi: 10.3389/fpsyt.2020.00518

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Copyright © 2020 Dethloff, Vargas, Elijah, Quinn, Park, Herzog, Müller, Gentry, Knight, Gonzalez, Dorrestein and Turck

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Paroxetine treatment revealed antidepressant-like and anxiolytic effects in DBA/2J mice. Chronic paroxetine (PARO) treatment for 14 days increased time of active coping (p = 1.5 E-7) in the Forced Swim Test (FST). Sample size was n = 10 for PARO group and n = 10 for Vehicle group. Bars represent mean ± SD, ***p < 0.001.