Figure 1.

Virus Constructs and AAV-Mediated Expression of CoChR-GFP following ON-BC Targeting and Ubiquitous RGC Expression

(A and B) Schematic depicting the virus constructs used for ON-BC targeting with the mGluR6 promoter (A) and ubiquitous RGC expression with the CAG promoter (B). (C) Virus vectors were injected into the eye through an intravitreal injection. (D and E) Representative immunofluorescence images show a broad expression of CoChR-GFP over the entire retina viewed in retinal whole mounts following ON-BC targeting (D) and RGC expression (E). The images were captured from TKO mice. Scale bar, 500 μm.