Table 2.
Cox proportional hazard model of all-cause mortality (event 88, n = 552).
| Risk factor | Univariable |
Multivariable |
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| PRECISE-DAPT score (low) | Ref. | Ref. | ||||
| Intermediate (vs. low) | 3.161 | 1.309–7.630 | <0.001 | 2.945 | 1.182–7.237 | 0.020 |
| High (vs. low) | 7.246 | 3.614–14.527 | <0.001 | 5.567 | 2.644–11.721 | <0.001 |
| Male gender | 0.832 | 0.514–1.349 | 0.456 | |||
| Body mass index | 0.899 | 0.844–0.959 | 0.001 | 0.989 | 0.922–1.061 | 0.759 |
| Current smoker | 0.568 | 0.373–0.864 | 0.008 | 0.940 | 0.590–1.497 | 0.793 |
| Hypertension | 1.040 | 0.499–2.167 | 0.917 | |||
| Diabetes | 1.042 | 0.686–1.584 | 0.846 | |||
| Dyslipidemia | 0.262 | 0.138–0.497 | <0.001 | 1.186 | 0.498–2.825 | 0.701 |
| Atrial fibrillation | 2.701 | 1.686–4.327 | <0.001 | 2.491 | 1.381–4.490 | 0.002 |
| Previous MI | 1.539 | 0.772–3.067 | 0.221 | |||
| Previous PCI | 1.203 | 0.603–2.399 | 0.599 | |||
| Previous CABG | 1.317 | 0.183–9.477 | 0.785 | |||
| LVEF | 0.985 | 0.975–0.994 | 0.002 | 0.988 | 0.977–1.000 | 0.049 |
| Number of diseased vessels | 1.411 | 0.921–2.163 | 0.114 | |||
| No-infarct LMT lesion | 1.993 | 0.918–4.327 | 0.081 | 1.592 | 0.712–3.557 | 0.257 |
| No-infarct CTO lesion | 2.743 | 1.615–4.659 | <0.001 | 2.477 | 1.387–4.423 | 0.002 |
| Culprit lesion (LAD) | 0.778 | 0.506–1.195 | 0.252 | |||
| Log peak CK | 0.924 | 0.577–1.481 | 0.744 | |||
| DES | 0.932 | 0.605–1.436 | 0.750 | |||
| BMS | 0.737 | 0.463–1.174 | 0.199 | |||
| Door to balloon time | 1.002 | 0.999–1.004 | 0.154 | |||
| Antiplatelets | 0.215 | 0.093–0.494 | <0.001 | 0.231 | 0.074–0.726 | 0.012 |
| β-blockers | 0.622 | 0.388–0.995 | 0.047 | 0.796 | 0.473–1.340 | 0.390 |
| RAS inhibitors | 0.491 | 0.289–0.835 | 0.009 | 0.551 | 0.303–1.001 | 0.051 |
| Statins | 0.249 | 0.159–0.390 | <0.001 | 0.483 | 0.263–0.890 | 0.020 |
| Anticoagulants | 1.562 | 0.977–2.498 | 0.062 | 0.877 | 0.497–1.550 | 0.652 |
PRECISE-DAPT, the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy; MI, myocardial infarction; PCI, percutaneous coronary intervention; CABG, coronary artery bypass graft; LVEF, left ventricular ejection fraction; LMT, left main trunk; CTO, chronic total occlusion; LAD, left anterior descending coronary artery; CK, creatine kinase; DES, drug eluting stent; BMS, bare metal stent; RAS, renin-angiotensin system.