Table 6.
Bioavailabilitya of NBBS following a single oral administration in rats and mice
Dose (mg/kg) | Male Rats | Female Rats | Male Mice | Female Mice |
---|---|---|---|---|
20 | 23 | 60 | 6 | 5 |
60 | 52 | 68 | 12 | 5 |
200 | 43 | 132 | 14 | 11 |
Bioavailability (%F) was calculated as AUC/Dose (oral) ÷ AUC/Dose (IV) x 100.