Table 3.
Overall and HIV stratified proportions of any squamous intraepithelial lesions by anal HPV genotypes (row percentages of number of SIL cases/person with or without HPV).
Any LSIL/HSIL |
|||
---|---|---|---|
Overall n/N (%) |
HIV-infected n/N (%) |
HIV-uninfected n/N (%) |
|
Multiple HPVs | |||
0 | 5/29 (17.2) | 0/2 (0.0) | 5/27 (18.5) |
1 | 23/38 (60.5) | 10/14 (71.4) | 13/24 (54.2) |
2–4 | 102/168 (60.7) | 69/101 (68.3) | 33/67 (49.3) |
5–11 | 66/107 (61.7) | 57/87 (65.5) | 9/20 (45.0) |
Multiple High-Risk HPVs | |||
0 | 44/90 (48.9) | 21/29 (72.4) | 23/61 (37.7) |
1 | 64/106 (60.4) | 41/68 (60.3) | 23/38 (60.5) |
2–3 | 68/111 (61.3) | 56/79 (70.9) | 12/32 (37.5) |
4–6 | 20/35 (57.1) | 18/28 (64.3) | 2/7 (28.6) |
Low-Risk HPV 6 and/or 11 | |||
No | 90/198 (45.5) | 60/103 (58.3) | 30/95 (31.6) |
Yes | 106/144 (73.6) | 76/101 (75.3) | 30/43 (69.8) |
High-Risk HPVs | |||
HPV16 | |||
No | 148/263 (56.3) | 98/146 (67.1) | 50/117 (42.7) |
Yes | 48/79 (60.8) | 38/58 (65.5) | 10/21 (47.6) |
HPV35 | |||
No | 170/293 (58.0) | 114/166 (68.7) | 56/127 (44.1) |
Yes | 26/49 (53.1) | 22/38 (57.9) | 4/11 (36.4) |
HPV39 | |||
No | 174/308 (56.5) | 117/177 (66.1) | 57/131 (43.5) |
Yes | 22/34 (64.7) | 19/27 (70.4) | 3/7 (42.9) |
HPV45 | |||
No | 154/280 (55.0) | 102/160 (63.8) | 52/120 (43.3) |
Yes | 42/62 (67.7) | 34/44 (77.3) | 8/18 (44.4) |
HPV51 | |||
No | 159/283 (56.2) | 107/162 (66.1) | 52/121 (43.0) |
Yes | 37/59 (62.7) | 29/42 (69.1) | 8/17 (47.1) |
HPV58 | |||
No | 183/318 (57.6) | 125/185 (67.6) | 58/133 (43.6) |
Yes | 13/24 (54.2) | 11/19 (57.9) | 2/5 (40.0) |
Low-Risk HPVs | |||
HPV6 | |||
No | 116/236 (49.2) | 77/129 (59.7) | 39/107 (36.5) |
Yes | 80/106 (75.5) | 59/75 (78.7) | 21/31 (67.7) |
HPV11 | |||
No | 150/280 (53.6) | 101/157 (64.3) | 49/123 (39.8) |
Yes | 46/62 (74.2) | 35/47 (74.5) | 11/15 (73.3) |
HPV42 | |||
No | 153/275 (55.6) | 100/151 (66.2) | 53/124 (42.7) |
Yes | 43/67 (64.2) | 36/53 (67.9) | 7/14 (50.0) |
HPV67 | |||
No | 166/293 (56.7) | 112/167 (67.1) | 54/126 (42.9) |
Yes | 30/49 (61.2) | 24/37 (64.9) | 6/12 (50.0) |
Abbreviations: SIL, squamous intraepithelial lesions; L/HSIL, low-grade/high-grade squamous intraepithelial lesions.
Bold type indicates statistical significance (p < 0.05) differences in the prevalence of SIL by HPVs overall and stratified by HIV using Pearson's Chi-Square and Fisher's exact tests.