Table 1.
Liver scores (median [range]) in a subset of aged GF controls and Hb-mono Swiss Webster mice at 13 to 14 mpi
| Hepatitis index (scale, 0–12) | Lobular (scale, 0–4) | Portal (scale, 0–4) | Interface (scale, 0–4) | Lobes with > 5 foci | |
| GF control males (n = 4) | 0.75 (0–1) | 0.5 (0–0.5) | 0 (0–0.5) | 0 (0) | 0 (0) |
| GF control females (n = 4) | 0.75 (0–1) | 0.5 (0–0.5) | 0 (0–0.5) | 0 (0) | 0 (0) |
| Hb-mono males (n = 4) | 1 (0–1) | 0.75 (0–1) | 0 (0–0.5) | 0 (0) | 0 (0) |
| Hb-mono females (n = 8) | 3.25 (0.5–7.5)a | 0.5 (0–2) | 1 (0.5–2.5)b | 0 (0–1) | 1 (0–4) |
a
P < 0.001 compared to all groups.
b
P < 0.05 compared to all groups.